Stem Cell Research, Exosomes, cell lines, cell culture media
Utilizing “-omics” Information to Inform Genome-wide Affiliation Research (GWASs) within the Osteoporosis Area Goal of evaluation: Osteoporosis constitutes a significant societal well being drawback. Genome-wide affiliation research (GWASs) have recognized over 1100 loci influencing bone mineral density (BMD); nevertheless, few of the causal genes have been recognized. Right here, we evaluation approaches that use “-omics” information and […]
Genome modifying in crops with MAD7 nuclease MAD7 is an engineered nuclease of the Class 2 sort V-A CRISPR-Cas (Cas12a/Cpf1) household with a low stage of homology to canonical Cas12a nucleases. It has been publicly launched as a royalty-free nuclease for each tutorial and industrial use. Right here, we exhibit that the CRISPR-MAD7 system can be […]
Genome evaluation to decipher syntrophy within the bacterial consortium ‘SCP’ for azo dye degradation Background: A bacterial consortium SCP comprising three bacterial members, viz. Stenotrophomonas acidaminiphila APG1, Pseudomonas stutzeri APG2 and Cellulomonas sp. APG4 was developed for degradation of the mono-azo dye, Reactive Blue 28. The genomic evaluation of every member of the SCP consortium was completed […]
A genome-wide affiliation examine of plasma phosphorylated tau181 Plasma phosphorylated tau at threonine-181 (P-tau181) demonstrates promise as an accessible blood-based biomarker particular to Alzheimer’s Illness (AD), with ranges not too long ago demonstrating excessive predictive accuracy for AD-relevant pathology. The genetic underpinnings of P-tau181 ranges, nevertheless, stay elusive. This examine presents the primary genome-wide affiliation examine […]